Recent research has highlighted a troubling reality: up to 50% of patients who survive sepsis die within two years of their initial recovery. While many patients survive the acute phase of sepsis, long-term mortality remains high due to several factors, including the development of new or recurring infections, organ damage, and chronic health conditions worsened by sepsis. These complications can include cardiovascular issues, cognitive decline, and repeated hospitalizations, all of which increase the risk of death even after the immediate infection has been treated.

One study, conducted by researchers, found that even with improvements in short-term survival rates, the long-term prognosis for sepsis survivors is bleak. The risk of death extends for years following initial hospitalization, especially among older adults and those with pre-existing health conditions​

To combat this, healthcare professionals are increasingly focusing on improving post-sepsis care, addressing underlying health issues, and monitoring patients closely after discharge. However, the long-lasting impacts of sepsis underline the need for better strategies to support survivors and reduce their long-term risk of mortality.