HPV: A Hidden Risk for Heart Health

Human Papillomavirus (HPV) is widely known for its association with various types of cancer, including cervical, throat, and anal cancer. However, recent research has uncovered an alarming connection between HPV and an increased risk of cardiovascular disease—an association that remains largely unknown to the general public.

A groundbreaking study presented at the American College of Cardiology’s Annual Scientific Session (ACC.25) analyzed data from nearly 250,000 individuals worldwide. The results showed that people infected with HPV are 40% more likely to develop cardiovascular disease and twice as likely to suffer from coronary artery disease compared to those without the virus. Even after adjusting for traditional risk factors such as smoking, diabetes, and high blood pressure, HPV infection was associated with a 33% increase in the likelihood of developing heart disease.

These findings suggest that HPV may contribute to heart disease through mechanisms unrelated to conventional risk factors. Researchers propose that chronic inflammation triggered by the virus could play a key role in damaging and obstructing arteries, thereby raising cardiovascular risk.

The implications of this research are significant—especially given that HPV is the most common sexually transmitted infection in the United States. Although HPV vaccination has mainly been promoted as a cancer prevention strategy, this new evidence supports the idea that vaccination might also help reduce the risk of heart disease.

Moreover, the results highlight the need for healthcare professionals to closely monitor the cardiovascular health of patients with HPV, especially those with additional risk factors like obesity. Comprehensive care and regular check-ups could be essential for detecting and preventing cardiac complications in this population.

In conclusion, while HPV has long been associated with cancer, emerging evidence links it to an increased risk of cardiovascular disease. This connection underscores the importance of preventive strategies—including vaccination and cardiovascular monitoring—to address the full range of health risks tied to this common infection.