After a cold and snowy winter, spring has arrived. Good news for spring lovers, but not so much for the 45 million Americans who suffer from seasonal allergies. Despite the fact that some suffer from allergies year-round, the symptoms usually get worse during this season. Especially if you live in one of the 100 worst cities for people with spring allergies.

The Asthma and Allergy Foundation of America released its annual ranking of ¨the most challenging places to live with spring allergies.” In 2015, Jackson, Miss., is the last place a person with allergies should be, followed by Louisville, Ky., and Oklahoma City, Okla.

Five cities in Pennsylvania made it to the ranking. Philadelphia is the worst city in the state for people with spring allergies and number 38 in the nation; Pittsburgh is number 57; Allentown 59; Scranton 62, and Harrisburg 70.

The ranking was made according to the daily amount of pollen in each cubic meter of air, the amount of allergy medication used by each patient in the city and the number of allergists per 10,000 patients.